Zvládání stresu v lékařských profesích

MUDr. Karel Nešpor, CSc.

Urol. praxi, 2014; 15(4): 147  

Urinary incontinence during pregnancy

MUDr.Ivan Huvar, CSc.

Urol. praxi, 2014; 15(4): 152-154  

Urinary incontinence is a symptom unexpectedly frequent in gravidity, affecting more than one half of pregnant women´s population.. It is more common in multiparous, than nulliparous women. The most common type of urinary incontinence during pregnancy is stress urinary incontinence (SUI), with prevalence 18,6–75 %, worsening with increasing gestational age to term. The cause of urinary incontinence in pregnancy is multifactorial and includes mechanical (expansion of growing uterus and increment increase of fetal weight), hormonal (progesteron, relaxin) and structural (total collagen content reduction and its tensile properties changes)...

Urinary tract infection in children and prevention

MUDr.Alexander Kolský, CSc., MUDr.Šárka Doležalová, MUDr.Jan Langer

Urol. praxi, 2014; 15(4): 155-158  

Urinary tract infection in children is a common complication in childhood. With exception of early infancy UTI affects more often girls. The aim of prevention is to prevent the recurrence of UTI. Antibiotics prophylaxis is now critically discussed. In the prevention of UTI are used cranberry, probiotics and Uro-Vaxom®.

Chemotherapy in urologic oncology; let us not be afraid to indicate treatment

MUDr.Jana Katolická, Ph.D.

Urol. praxi, 2014; 15(4): 159-161  

Chemotherapy in urology is an important adjunct to locoregional procedures, i.e. surgical treatment and radiotherapy, while, in particular, being an indispensable therapeutic method in metastatic or locally advanced tumours. Chemotherapy can extend life; when administered, however, it has a number of adverse effects. Novel agents used in the second-line therapy for metastatic disease – cabazitaxel in castration-resistant prostate cancer and vinflunine in urothelial carcinoma of the bladder – have become standard treatment because of their benefit.

Is the current LUTS/BPH therapy sufficient?

MUDr.Libor Zámečník, Ph.D., FEBU, FECSM

Urol. praxi, 2014; 15(4): 162-165  

This article summarizes treatment options for lower urinary tract symptoms in combination with symptoms of overactive bladder.

Prostate and vitamine D

prof.MUDr.RNDr.Luboslav Stárka, DrSc., MUDr.Božena Kalvachová, CSc.

Urol. praxi, 2014; 15(4): 166-168  

Recently, there is accumulated knowledge that vitamin D may modify immune function, cell proliferation, differentiation and apoptosis and act in many other functions of body organs. Vitamin D deficiency has been associated with numerous health outcomes, including benign prostate hyperplasia and prostate carcinoma. Clinical studies with patients treated for these diseases with addition of vitamin D or its analogues should show the benefits of vitamin D supplementation. In spite of some success of vitamin D supplementation the results of studies on men with prostatic diseases were less promising than in experiments in vitro or on animals. Notwithstanding,...

Patient with locally advanced adenocarcinoma of the rectosigmoid in the urology clinic

MUDr.Monika Žižlavská, MUDr.Martin Drábek, MUDr.Zdeněk Lavička

Urol. praxi, 2014; 15(4): 177-179  

Colorectal cancer is a disease of civilization. Its worldwide incidence depends on the development of the country. The current studies clearly show a significantly higher incidence of the disease in the developed countries. Diagnosis is often delayed, early stages of the disease are usually asymptomatic. Therefore, about 25 % of cases are diagnosed as an already advanced disesase. In the case of locally advanced pelvic tumors without evidence of metastatic disease is indicated by en bloc pelvic exenteration. The surgery and postoperative period are especially severe burden on the organism. Good condition and the patient’s informed consent...

The ileal ureter substitution with the lower calix anastomosis

MUDr.Alena Kosařová, MUDr.Hynek Šafránek, MUDr.Lukáš Holub, doc.MUDr.Miloš Broďák, Ph.D.

Urol. praxi, 2014; 15(4): 180-181  

The abruption of the ureter is rare, but serious complication of ureteroscopic stone removal. In case of serious damage of the ureter without possibility of correction, it is recommended the ileal ureter substitution. We present the ileal ureter replacement with the calix-ileal anastomosis, due to the scarred intrarenal pelvis. Pre-operative period was complicated by recurrent urinary tract infections. Postoperative period was out of the complications for long time.

Xp 11.2 translocation renal cell carcinoma

MUDr.Zuzana Kováčová-Majerová, FEBU, MUDr.Radomír Zachoval, Ph.D., Dr.h.c., MUDr.Yaroslav Andriychuk

Urol. praxi, 2014; 15(4): 182-184  

A case report of a young patient with an image of a renal colic, with a finding of a huge renal tumour. A metastasis in a regional lymph node was present at time of diagnosis. The patient has undergone a radical nephrectomy and lymphadenectomy with a histological finding of a renal cell carcinoma with a Xp 11,2 translocation, pT2a N1 Mo G3. Patient has started a target therapy as a part of a clinical trial and he is without signs of metastases.

Treating urinary incontinence with botulinum toxin

Mgr.Nataša Sochorová, Miroslava Šefčíková, MUDr.Eva Burešová

Urol. praxi, 2014; 15(4): 186-189  

Botulinum toxin, also known as “sausage poison”, is a toxic substance that is naturally produced by the bacterium Clostridium botulinum. Poisoning with botulinum toxin, which can be ingested with contaminated food, has very serious consequences and can even end fatally. If botulinum toxin is subjected to heat treatment, its poisonous effects are destroyed.

Zpráva ze semináře Karcinom prostaty - nové pohledy na diagnostiku a léčbu v roce 2014

doc. MUDr. Miroslav Hanuš, CSc.,, MUDr. Michaela Matoušková

Urol. praxi, 2014; 15(4): 193-198  

Avanafil - a novel phosphodiesterase inhibitor for treating erectile dysfunction in clinical practice.

MUDr.Lukáš Bittner, FEBU, FECSM

Urol. praxi, 2014; 15(4): 170-172  

How is it different from the established molecules? Phosphodiesterase-5 inhibitors are drugs of choice for erectile dysfunction treatment. Now, there is new one molecule on the marketavanafil. What is the difference between avanafil and other PDE-5 inhibitors?

Fosfomycin in the treatment of urinary tract infections

MUDr.Jiří Slíva, Ph.D.

Urol. praxi, 2014; 15(4): 173-174  

Uncomplicated urinary tract infections in adults are predominantly caused by E. coli, followed by staphylococci and other bacteria. This article deals in brief the molecule of fosfomycin, which is currently recommended as drug of choice in this indication. Additionally, pharmacodynamic properties, EAU recommendations, risk of resistance and compliance to proposed therapy are discussed.

Brusinky v léčbě a prevenci infekcí dolních močových cest

Urol. praxi, 2014; 15(4): 191-192