Urol. praxi. 2024;25(3):130-135 | DOI: 10.36290/uro.2024.056

Hybrid imaging methods in diagnostics of prostatic carcinoma

prof. MUDr. Jiří Ferda, Ph.D., MUDr. Eva Ferdová
Klinika zobrazovacích metod LF UK a FN v Plzni

Imaging of the prostate tumour´s own tissue is using standard tumour imaging approaches remains difficult, the imaging using contrast enhanced computed tomography and also the hybrid imaging using PET/CT with the application of the 18F-fluorodeoxyglucose is insufficient. Magnetic resonance imaging is useful in detection of prostate cancer in patients with elevated prostatic specific antigen (PSA) and/or with increased prostate health index (PHI). Currently, it is possible to use combination of radiological and nuclear medicine methods - hybrid positron emission tomography combined with computed tomography (PET/CT) or with magnetic resonance imaging (PET/MRI) with the application of 18F-fluorocholine (FCH), 18F-fluciclovine, 18F-natriumfluoride (18F-NaF) or 68Ga-PSMA-11 (ligand of prostatic specific membrane antigen) in detection, staging or restaging of prostate carcinoma. PET/CT or PET/MRI with the application of 68Ga-PSMA-11 represents current optimal method for staging, restaging and evaluation of prostate cancer therapy response.

Keywords: prostate cancer, PET/MRI, PET/CT, 18F-fluorocholine, 18F-fluciclovine, 18F-natri­umfluoride, 68Ga-PSMA-11.

Accepted: October 1, 2024; Published: November 14, 2024  Show citation

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Ferda J, Ferdová E. Hybrid imaging methods in diagnostics of prostatic carcinoma. Urol. praxi. 2024;25(3):130-135. doi: 10.36290/uro.2024.056.
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