Urol. praxi, 2014; 15(4): 182-184

Xp 11.2 translocation renal cell carcinoma

MUDr.Zuzana Kováčová-Majerová, FEBU, MUDr.Radomír Zachoval, Ph.D., Dr.h.c., MUDr.Yaroslav Andriychuk
Urologické oddělení nemocnice Třebíč

A case report of a young patient with an image of a renal colic, with a finding of a huge renal tumour. A metastasis in a regional lymph

node was present at time of diagnosis. The patient has undergone a radical nephrectomy and lymphadenectomy with a histological

finding of a renal cell carcinoma with a Xp 11,2 translocation, pT2a N1 Mo G3. Patient has started a target therapy as a part of a clinical

trial and he is without signs of metastases.

Keywords: Xp 11,2 translocation renal cell carcinoma, target therapy

Published: October 1, 2014  Show citation

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Kováčová-Majerová Z, Zachoval R, Andriychuk Y. Xp 11.2 translocation renal cell carcinoma. Urol. praxi. 2014;15(4):182-184.
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References

  1. Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin. 2011 Mar-Apr; 61(2): 69-90. Go to original source... Go to PubMed...
  2. Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010 Mar; 46(4): 765-781. Go to original source... Go to PubMed...
  3. Landis SH, Murray T, Bolden S, et al. Cancer statistics: 1999. CA Cancer J Clin, 1999; 49: 8-31. Go to original source... Go to PubMed...
  4. Novotvary 2007 ČR. ÚZIS ČR 2010. www.svod.cz.
  5. Kawaciuk I, Hyršl L, Dušek P, Jarolím L, et al. Rozměr nádoru, staging a grading malignity v prognóze karcinomu ledviny. Ces. Urol 2005; 9(3): 42.
  6. Lonser RR, Glenn GM, Walther MM, Chew EY, Libutti SK, Linehan WM, et al. Von Hippel-Lindau disease. Lancet 2003; 361: 2059-2067. Go to original source... Go to PubMed...
  7. Branžovský J, Martínek P, Baulet K. Využití molekulární genetiky v diferenciální diagnostice nádorů ledvin. Ces Urol 2012; 16(4): 214-221.
  8. Camparo P, Vailiu V, Molinie V, et al. Renal translocation carcinomas. Clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literature. Am J Surg pathol 2008; 35: 656-670. Go to original source... Go to PubMed...
  9. Salles PGO, Soto M jr. Kidney carcinoma associated with Xp11.2 translocation/TFE3 (ASPL-TFE3) gen vision. Int Braz J Urol 2005; 31: 251-255. Go to original source... Go to PubMed...
  10. Argani P, Olgac S, Tickoo SK, et al. Xp11 translocation renal cell carcinoma in adults: expanded clinical, pathological, and genetic spectrum. Am J Surg Pathol 2007; 31: 1149-1160. Go to original source... Go to PubMed...
  11. Podhola M. Karcinom ledvin dospělých. Onkologie 2009; 3(2): 80-82.
  12. Kaelin WG. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2002; 2: 673-682. Go to original source... Go to PubMed...
  13. Hora M, Hes O, Eret V, et al. Translokační renální karcinom Xp11.2 typu ASPL/TFE3.Ces Urol 2008; 12(3): 186-193.
  14. Szakácsová, M. Nádory ledvin v Přehled novinek z 9. konference ESOU. Ces Urol 2012; 16(2): 130-136.
  15. Študentová H, Algoritmus léčby metastatického karcinomu ledviny. Urol. praxi, 2011; 12(3): 152-157.




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