Urol. praxi, 2014; 15(4): 166-168

Prostate and vitamine D

prof.MUDr.RNDr.Luboslav Stárka, DrSc., MUDr.Božena Kalvachová, CSc.
Endokrinologický ústav, Praha

Recently, there is accumulated knowledge that vitamin D may modify immune function, cell proliferation, differentiation and apoptosis

and act in many other functions of body organs. Vitamin D deficiency has been associated with numerous health outcomes, including

benign prostate hyperplasia and prostate carcinoma. Clinical studies with patients treated for these diseases with addition of vitamin

D or its analogues should show the benefits of vitamin D supplementation. In spite of some success of vitamin D supplementation the

results of studies on men with prostatic diseases were less promising than in experiments in vitro or on animals. Notwithstanding, in

androgen-deprivation therapy of prostate carcinoma vitamin D supplementation appears to be a regular part of the treatment.

Keywords: vitamine D, calcidiol, calcitriol, BPH, prostate carcinoma

Published: October 1, 2014  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Stárka L, Kalvachová B. Prostate and vitamine D. Urol. praxi. 2014;15(4):166-168.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Muszkat P, Camargo MB, Griz LH, Lazaretti-Castro M. Evidence-based non-skeletal actions of vitamin D. Arg Bras Endocrinol Metabol. 2010; 54(2): 110-117. Go to original source... Go to PubMed...
    2. Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, et al. Vitamin D: beyond bone. Ann N Y Acad Sci. 2013; 1287: 45-58. Go to original source... Go to PubMed...
    3. Basit S. Vitamin D in health and disease: a literature review. Br J Biomed Sci. 2013; 70(4): 161-72. Go to original source... Go to PubMed...
    4. Kalvachová B. Vitamin D - nové poznatky a endokrinní mikrosystémy kalcitriolu. Osteol. Bull. 2007; 12(2): 62-67.
    5. Cirmanová V, Kančeva R, Vondra K, Bayer M. Renesance vitaminu D. DMEV 2010; 13(3): 139-145.
    6. Bayer M. Vitamin D v peditarické praxi. Postgrad. Med. 2010; 12(příloha 2): 39-43.
    7. www.vnitrnilekarstvi.cz Vnitřní lékařství - příloha Vitamin D, 2012; 58(5).
    8. Slíva J. Vitamin D významný nejenom v metabolizmu kalcia. Remedia 2013; 23(4): 278-281.
    9. Woo TC, Choo R, Jamieson M. Potential role of vitamin D (cholecalciferol) in patients with PSA relapse after definitive therapy. Nutr Cancer 2005; 51(1): 32-36. Go to original source... Go to PubMed...
    10. Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Feb 11. pii: S1074-5521 (14)00024-6. Go to original source... Go to PubMed...
    11. Bílek R. Vitamin D a jeho cirkulující metabolity. V. Stárka L. Pokroky v endokrinologii. Maxdorf-Jesenius, Praha 2007: 192-200.
    12. Swami S, AV, Feldman D. Vitamin D metabolism and action in the prostate: Implications for health and disease. Mol Cell Endocrinol. 2011; 347(1-2): 61-69. Go to original source... Go to PubMed...
    13. Zitterman A. The estimated benefits of vitamin D for Germany. Mol Nutr Food Res. 2010; 54(8): 1164-1171. Go to original source... Go to PubMed...
    14. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011; 96(1): 53-58. Go to original source... Go to PubMed...
    15. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, et al. Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. J Clin Endocrinol Metab. 2012; 97(4): 1153-1158. Go to original source... Go to PubMed...
    16. Donkena KV, Young CY. Vitamin D, sunlight and prostate cancer risk. Adv Prev Med. 2011; 2011: 281863. Go to original source... Go to PubMed...
    17. Bikle DD. Vitamin D and cancer: the promise not yet fulfilled. Endocrine. 2014 Jan 9. Go to original source... Go to PubMed...
    18. Prietl B, Treiber G, Pieber TR, Amrein K. Vitamin D and immune function. Nutrients. 2013; 5(7): 2502-2521. Go to original source... Go to PubMed...
    19. Reichrath J, Reichrath S. The relevance of the vitamin D endocrine system (VDES) for tumorigenesis, prevention, and treatment of non-melanoma skin cancer (NMSC): Present concepts and future perspectives. Dermatoendocrinol. 2013; 5(1): 38-50. Go to original source... Go to PubMed...
    20. Girgis CM, Clifton-Bligh RJ, Turner N, Lau SL, Gunton JE. Effects of vitamin D in skeletal muscle: falls, strength, athletic performance and insulin sensitivity. Clin Endocrinol (Oxf). 2014; 80(2): 169-181. Go to original source... Go to PubMed...
    21. Dong J, Lau CW, Wong SL, Huang Y. Cardiovascular benefits of vitamin D. Acta Physiol. Sin. (Sheng Li Xue Bao). 2014; 66(1): 30-36.
    22. Kunadian V, Ford GA, Bawamia B, Qiu W, Manson JE. Vitamin D deficiency and coronary artery disease: A review of the evidence. Am Heart J. 2014; 167(3): 283-291. Go to original source... Go to PubMed...
    23. Guan X, Yang H, Zhang W, Wang H, Liao L. Vitamin D receptor and its protective role in diabetic nephropathy. Chin Med J (Engl). 2014; 127(2): 365-369. Go to PubMed...
    24. Mitri J, Pittas AG. Vitamin D and Diabetes. Endocrinol Metab Clin North Am. 2014; 43(1): 205-232. Go to original source... Go to PubMed...
    25. James E, Dobson R, Kuhle J, Baker D, Giovannoni G, Ramagopalan SV. The effect of vitamin D-related interventions on multiple sclerosis relapses: a meta-analysis. Mult Scler. 2013; 19(12): 1571-1579. Go to original source... Go to PubMed...
    26. Annweiler C, Llewellyn DJ, Beauchet O. Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis. 2013; 33(3): 659-674. Go to original source... Go to PubMed...
    27. Annweiler C, Montero-Odasso M, Llewellyn DJ, Richard-Devantoy S, Duque G, Beauchet O. Meta-analysis of memory and executive dysfunctions in relation to vitamin D. J Alzheimers Dis. 2013; 37(1): 147-171. Go to original source... Go to PubMed...
    28. Balion C, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, Llewellyn DJ, Raina P. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology. 2012; 79(13): 1397-1405. Go to original source... Go to PubMed...
    29. Kristal AR, Arnold KB, Schenk JM, Neuhouser ML, Goodman P, et al. Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial. Am J Epidemiol, 2008; 167(8): 925-934. Go to original source... Go to PubMed...
    30. Colli E, Rigatti P, Montorsi F, Artibani W, Petta S, et al. BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial. Eur Urol. 2006; 49(1): 82-86. Go to original source... Go to PubMed...
    31. Espinosa G, Esposito R, Kazzazi A, Djavan B. Vitamin D and benign prostatic hyperplasia - a review. Can J Urol. 2013; 20(4): 6820-6825. Go to PubMed...
    32. Szendroi A, Speer G, Tabak A, Kosa JP, Nyirady P, et al. The role of vitamin D, estrogen, calcium sensing receptor genotypes and serum calcium in the pathogenesis of prostate cancer. Can J Urol. 2011; 18(3): 5710-5716.
    33. Der T, Bailey BA, Youssef D, Manning T, Grant WB, Peiris AN. Vitamin D and prostate cancer survival in eterans. Mil Med. 2014; 179(1): 81-84. Go to original source... Go to PubMed...
    34. Wilczek H, Vachalovský V. Význam vitaminu D u karcinomu prostaty. Cas Lek Cesk. 1996; 135(22): 716-718.
    35. Yaturu S, Zdunek S, Youngberg B. Vitamin d levels in subjects with prostate cancer compared to age-matched controls. Prostate Cancer. 2012; 2012: 524206. Go to original source... Go to PubMed...
    36. Ahn J, Peters U, Albanes D, Purdue MP, Abnet CC, et al. Serum vitamin D concentration and prostate cancer risk: a nested case-control study. J Natl Cancer Inst. 2008100(11): 796-804. Go to original source...
    37. Grossmann M, Hamilton EJ, Gilfillan C, Bolton D, Joon DL, Zajac JD. Bone and metabolic health in patients with non-metastatic prostate cancer who are receiving androgen deprivation therapy. Med J Aust. 2011; 194(6): 301-306. Go to original source... Go to PubMed...
    38. Datta M, Schwartz GG. Calcium and vitamin D supplementation durin androgen deprivation therapy for prostate cancer: a critical review. Oncologist. 2012; 17(9): 1171-1179. Go to original source... Go to PubMed...

    Return to the content


    Urology for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.