Urol. praxi, 2011; 12(3): 180-182

Wobenzym.

MUDr.Miroslav Förstl¹, Bc.Miroslava Förstlová¹, doc.MUDr.Olga Ryšková, CSc.¹, MUDr.Ivo Kalousek, Ph.D.², MUDr.Pavel Navrátil, CSc.³

¹ Ústav klinické mikrobiologie FN a LF UK Hradec Králové

² Porodnická a gynekologická klinika FN a LF UK Hradec Králové

³ Urologická klinika FN a LF UK Hradec Králové

Enzyme therapy for urogenital infections with Chlamydia trachomatis

The aim of the paper is to publish the results of the effect of antibiotic therapy (ATB) alone as well as of its combination with systemic

enzyme therapy in acute uncomplicated urogenital infections with Chlamydia trachomatis. We have previously published the results

of the treatment with azithromycin alone (AZT: 1 × 500 mg/day for 3 days) and of the same treatment in combination with Wobenzym

(W: 3 × 5 tablets/day for 14 days). Now, we present the results of our second study where virtually the same was investigated, i. e. a combination

of the same enzyme therapy with another ATB, clarithromycin (CLR: 500 mg tablets without controlled release twice daily for 14 days).

The success rate of the treatment with CLR alone (again based on the results of a follow-up smear 4 weeks after cessation of ATB treatment;

antigen detection using the immunofluorescence method) in men (n = 16) was identical to that with AZT, namely 62.5 %; however,

in combined therapy (n = 16), the success rate even increased from 75 % for AZT + W to 87.5 % for CLR + W. By contrast, in women the

success rates of treatment with CLR alone (n = 16) and with CLR + W (n = 16) were zero and this issue needs to be addressed further.

Wobenzym.

Keywords: Chlamydia trachomatis, acute uncomplicated urogenital infections, azithromycin, clarithromycin, systemic enzyme therapy,

Published: June 1, 2011  Show citation