Psychohygiena pro zdravotníky (nejen) v době koronavirové

PhDr. Adam Suchý, doc. PhDr. Miroslav Světlák, Ph.D.

Urol. praxi. 2020;21(2):55  

New trends in diagnostics and therapy of urinary stones - the role of CT examination

MUDr. Milan Král, Ph.D., MUDr. Filip Čtvrtlík, Ph.D., Ing. Jaromír Ptáček, Ph.D., MUDr. František Hruška, FEBU, MUDr. Michaela Motolová

Urol. praxi. 2020;21(2):57-61 | DOI: 10.36290/uro.2020.024  

Diagnostics of urinary stones is an integral and everyday part of urologist´s activity. It requires essential cooperation with radiologist. CT enables not only the identification of the true cause of renal colic but it can also assess basic stone characteristic - size, number, location. Moreover, the CT scan can predict stone composition, its density, homogenity and predict the efficacy of the planned treatment. The aim of this article is to enlighten the basics of CT examination to ordinary urologist.

Uric acid from the perspective of kidney disease

MUDr. Jiří Kladenský

Urol. praxi. 2020;21(2):62-66 | DOI: 10.36290/uro.2020.014  

Uric acid (UA) is the end product of purine metabolism in man. There are three sources of UA in man: food nucleotides, degradation of tissue nucleoproteins, and biosynthesis. UA is eliminated by the kidneys in 75-80%, with the remainder being excreted from the body by the gastrointestinal tract and through perspiration. Plasma UA concentration depends on dietary purine intake, intensity of its intrinsic formation, and its elimination rate. Elevated levels of UA in the blood (hyperuricaemia) and increased urinary UA excretion (hyperuricosuria) are of clinical significance. In the case of disorders of UA metabolism, hyperuricaemia tends to be the major...

Probiotics and bacterial lysates as an alternative non-antibiotic strategy in supportive treatment of uncomplicated urinary tract infections

PharmDr. Bc. Hana Kotolová, Ph.D.

Urol. praxi. 2020;21(2):67-71 | DOI: 10.36290/uro.2020.025  

Urinary tract infections, along with respiratory tract infections, are the most frequent inflammatory diseases in man. Given the current situation of antibiotic resistance, non-antibiotic treatment strategies are also recommended in uncomplicated urinary tract infections. Non-antibiotic strategies can effectively be implemented by recommending appropriate daily routine measures supported by a well-chosen over-the-counter medicinal product, a healing tea blend, or a food supplement. Current knowledge of the microbiome as a modulator of a number of diseases has brought the anticipated positive use of probiotics and bacterial lysates as an interesting...

Androgen deficiency in men and its treatment with testosterone in practice

MUDr. Libor Zámečník, Ph.D., FEBU, FECSM

Urol. praxi. 2020;21(2):72-79 | DOI: 10.36290/uro.2020.022  

The author provides information on the diagnosis of male hypogonadism and practical testosterone replacement treatment - including the latest guidelines for the treatment and monitoring of patients according to the European Association of Urology.

Drug interactions in urology - what to watch out for

PharmDr. Josef Suchopár, MUDr. Michal Prokeš, Štěpán Suchopár

Urol. praxi. 2020;21(2):80-86 | DOI: 10.36290/uro.2020.026  

Drug interactions are a problem in all medical disciplines including urology. A number of typically urological drugs such as drugs for the treatment of overactive bladder, benign prostatic hyperplasia or erectile dysfunction are substrates of CYP3A4 and the P-glycoprotein transport system. Combination of these drugs with inhibitors or inducers of CYP3A4 or P-glycoprotein can either lead to adverse events or reduce the effect to failure. In addition, manufacturers often recommend changes in drug dosage when combined with CYP3A4 inhibitors and it may be difficult for physicians to navigate such recommendations.

Retroperitoneal lymfatic nodule metastasis of seminoma with "burned-out" primary focus in the left testicle

MUDr. Patrik Stegmann, MUDr. Michal Grepl, Ph.D., MUDr. Jaroslav Hynčica

Urol. praxi. 2020;21(2):87-88 | DOI: 10.36290/uro.2020.027  

This case report introduce a patient who was admitted to urological department with left sided symptomatology of renal colic. Ultrasound and computed tomography findings showed retroperitoneal tumor with diameter 7 × 6 × 8 cm. After finishing all examinations was the final diagnose a retroperitoneal lymfatic nodule metastasis of seminoma with burned-out primary focus in the left testicle.

Surgical solutions blocking pyelolithiasis and casting nephrolithiasis of the right kidney and left kidney tumor in a patient with a horseshoe kidney

MUDr. Kateřina Šebková, MUDr. Michal Kotlář, MUDr. Otakar Mareš, MUDr. Jaroslava Drechslerová, CSc., MUDr. Marta Hósová

Urol. praxi. 2020;21(2):89-91 | DOI: 10.36290/uro.2020.028  

We present a case report describing a patient a with a horseshoe kidney who experienced several complications arising in the field of this congenital developmental defekt. We addressed blocking, bulky nephrolithiasis in the right kidney and bulky tumor in the left kidney. We first combined the endoscopic solution of lithiasis and then with the distance of removal of the left horseshoe tumor from transperitoneal open access. There may be a problem with the surgical approach to the horseshoe kidneys due to their atypical positions and vascular supply, where we could earn a balance as to how sufficient functional renal parenchyma is possible, even with...

Liposarcoma of the spermatic cord with early pelvic lymph node metastasis with paraneoplastic trombosis of left lower limb

MUDr. Veronika Kaľatová, MUDr. Jan Pokorný, FEBU, MBA, MUDr. Ernest Jirásek

Urol. praxi. 2020;21(2):92-93 | DOI: 10.36290/uro.2019.080  

Paratesticular tumors are relatively rare malignant diseases. We present a case report of a 66-year-old patient diagnosed with spermatic cord liposarcoma with early pelvic lymph node metastasis and subsequent paraneoplastic thrombosis of the left lower limb.

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Urol. praxi. 2020;21(2)