Budoucnost asistivních technologií v medicíně

doc. Ing. Lenka Lhotská, CSc.

Urol. praxi. 2018;19(5):207  

Is age the limitation of metastatic treatment prostate cancer?

MUDr. Jana Katolická, Ph.D.

Urol. praxi. 2018;19(5):210-216  

The median age of men with prostate cancer is 67,5 years. We have evidence-based information about elderly with metastaticprostate cancer in clinical trials. The age alone in not a contraindication for ARTA therapy (abiraterone acetate + prednisone,enzalutamide) and chemotherapy (docxetaxel,cabazitaxel). The radium-223 is a therapeutic options for bone metastases. The allpossible interactions of treatment should be monitored.

The role of extracorporeal shock wave lithotripsy in modern urological stone therapy

MUDr. Michaela Motolová

Urol. praxi. 2018;19(5):218-222 | DOI: 10.36290/uro.2018.091  

The global prevalence of urolithiasis is growing and requires safety, effective and cost-acceptable therapy. The discovery od ESWLwas a revolution in mangment of upper urinary tract stones – it has led to a definitive abandonment of open surgery proceduresand brought establishment of non- / minimal invasive treatment era. The leaders of nowadays – endourological techniques continuallydepreciate the importance of ESWL.

Acute scrotum in children – diagnosis and treatment

MUDr. Šimon Reich, MUDr. Jan Kříž, MUDr. Hana Kolářová, MUDr. Jan Trachta

Urol. praxi. 2018;19(5):223-227  

Acute scrotum is an emergency that every pediatrician has to face. Differential diagnosis is difficult to distinguish even for an experiencedclinician. Also there are many contradictory facts and recommendations concerning the acute scrotum in the literature.The following article summarizes recent findings and evidence based medicine recommendations without repeating well-knownanatomy and physiology facts. It concentrates upon the contradictory points of diagnosis and management of the acute scrotumin children. The authors based the article on 2015 ESPU guidelines, UpToDate® server, PubMed studies and reviews and their ownclinical experience....

Consequences of genitourinary malignancies therapy on cardiovascular system

prof. MUDr. Beata Mladosievičová, CSc., MUDr. Lucia Petríková, RNDr. Zuzana Poljak Valášková, Ph.D.

Urol. praxi. 2018;19(5):228-232 | DOI: 10.36290/uro.2018.093  

Cardiovascular toxicity induced by conventional anticancer drugs (anthracyclines and platinum compounds) has historically beena relevant issue of patients with genitourinary malignancies. In addition, targeted and androgen-deprivation therapies can alsoinduce cardiotoxicity in these patients. Immune checkpoint inhibitors are a novel class of effective antineoplastic drugs withcardiotoxicity used in patients with urogenital malignancies. Cardiotoxicity has been long underestimated in clinical practice,but during the last years significant number of patients with serious cardiovascular complications during or after completionof anticancer therapy have...

Sexual dysfunction after radical uro-oncological procedures

MUDr. Vladimír Kubíček, CSc.

Urol. praxi. 2018;19(5):234-236 | DOI: 10.36290/uro.2018.094  

The concept of penile rehabilitation revolves around protection of erectile tissue – cavernosal smooth muscle and endothelium,during the phase when the cavernous nerves are non-functioning or functioning poorly. The aim of the rehabilitation is to preserveerectile tisuue such that the patient has the best chance of returning close to his baseline erectile function.

Autocastration as a severe manifestation of schizofrenia

MUDr. Jakub Baron, MUDr. Rostislav Kuldan, MUDr. Jana Bocková

Urol. praxi. 2018;19(5):244-245 | DOI: 10.36290/uro.2018.096  

The authors present a case report of a patient who underwent a self-orchiectomy of his left testicle at home with the need of a subsequentsurgical revision. Afterwards the authors describe the procedure of hospitalization with a following transfer to a psychiatric department.

Urinary schistosomiasis in differential diagnosis of microhematuria in a young man

MUDr. Tereza Albínová, doc. MUDr. Jan Krhut, Ph.D., MUDr. Radek Sýkora, MUDr. Lubomíra Hozáková, MUDr. Radoslava Tomanová

Urol. praxi. 2018;19(5):246-248 | DOI: 10.36290/uro.2018.097  

Schistosomiasis is the second most widespread tropical desease after malaria. This infection occurs as an infection imported from endemicareas into the Czech Republic. Swimming in the contaminated water is a risk factor of the schistosomiasis. The presented case report describesthe case of a young 37-years-old man with a positive traveler's history and repeated asymptomatic microhemathuria accompaniedby antibiotic non-responsive leukocytes. According to the completed CT examination and cystoscopy, suspicion of bladder cancer wasreported. Transurethral resection of suspected bladder tumor was performed, histologically parasite bodies were found in the...

Mixed Epithelial and Stromal Tumor of the Kidney

MUDr. Pavel Navrátil, MUDr. Lukáš Krbal, doc. MUDr. Miloš Broďák, Ph.D.

Urol. praxi. 2018;19(5):249-250 | DOI: 10.36290/uro.2018.098  

Mixed epithelial and stromal tumors of the kidney are relatively rare benign tumors with female predominance. Imaging methodsshow multiple cystic and solid areas and are not diagnostic. As category Bosniak III or IV are threated surgically. Histopathologicallythey show mesenchymal and epithelial components with characteristic immunohistochemical evidence of estrogen andprogesterone receptors. This article presents a case report with a review of literature.

Vitamin D3, its aspect and possible use for urology

doc. MUDr. Juraj Fillo, PhD., MPH, MUDr. Michaela Levčíková

Urol. praxi. 2018;19(5):239-243  

There is increasing evidence from experimental and epidemiological studies suggesting that vitamin D deficiency may be thecause of increased morbidity, cancer and associated mortality. The vitamin D deficit is very widespread and most of the populationin Europe, especially in the northern part, suffers from a deficiency. Promising knowledge about vitamin D3 in prevention andtreatment has been known for over 30 years. Significant results with D3 supplementation were achieved for colorectal cancerand breast cancer. The thesis deals with the effects of vitamin D3 on prostate cancer. The results are controversial. Recommendeddoses in various studies include...