Urol. praxi, 2011; 12(2): 111-113
Prevention and treatment of erectile dysfunction following radical prostatectomy
- Urologické odd., Nemocnice Třebíč
With increasing incidents of prostate cancer, the number of curative, effective radical prostatectomies carried out through various
means has been rising. The most frequent complications in the postoperative phase are urine incontinence and erectile dysfunction. For
sexually-active men, losing their ability to have an erection can lead to a marked decline in their quality of life. Numerous publications
confirm the benefits of both urologists and their patients taking an active stance towards this problem. A single, standard strategy for
addressing the issue does not exist; apart from surgical techniques, methods include postoperative care and the regular use of various
remedies to achieve an erection. The authors focused on the current options available for the prevention and treatment of erectile
dysfunction after radical prostatectomy.
Keywords: prostate cancer, radical prostatectomy, erectile dysfunction
Published: April 1, 2011 Show citation
References
- Ústav zdravotnických informací a statistiky ČR. www.uzis.cz.
- Aus G, Abbou CC, Bolla M, et al. EAU guidelines on prostate cancer. Eur Urol 2005; 48: 546-551.
Go to original source... 
Go to PubMed... - Walsh PC. Anatomic radiál prostatectomy: evolution of the surgical technics. J Urol 1998. Go to original source... Go to PubMed...
- Jarolim J, Kawaciuk P, Hanek L, et al. Funkční výsledky radikálních retropubických prostatektomií. Čes urol 2005; 9(1): 20-25.
- Nandipati KC, Raina R, Agarwal A, et al. Erectile dysfunction following radical retropubic prostatectomy: epidemiology, pathophysiology and farmacological management. Drugs Aging 2006; 23: 101-117. Go to original source... Go to PubMed...
- Moreland RB, Albadawi H, Bratton C, et al. O-dependent prostanoid synthesis activates functional PGE receptors on corpus cavernosum smooth muscle. Am J physiol Heart Circ Physiol 2001; 281(2): 552-558. Go to original source... Go to PubMed...
- Breza J, Aboseif SR, Orvis BR, et al. Detailed anatomy of penile neurovascular structures - surgical signifikance J. Urol 1989; 141: 437-443. Go to original source... Go to PubMed...
- Sutorý M. Erektilní dysfunkce po operacích v malé pánvi. Současné možnosti léčby/rehabilitace penisu. Urolog. pro Praxi, 2009; 10(6): 328-331.
- Montorsi F, Guazzoliní G, Strambul L, et al. Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol, 1997; 158: 1408-1410. Go to original source... Go to PubMed...
- Montorsi F, Nathan HP, McCullough A, et al. Tadalafil in the treatment of erectile dysfunction following bilateral nerve sparing radical retropubic prostatectomy: a randomized, double blind, placebo controlled trial. J Urol, 2004; 172: 1036-1041. Go to original source... Go to PubMed...
- Zippe CD, Kedia S, Kedia AW, et al. Sildenafil citrate (Viagra) after radical retropubic prostatectomy: pro. Urology, 1999; 54: 583-586. Go to PubMed...
- Padma-Nathan H, McCullough A, Guiliano F, et al. Postoperative nightly administration of sildenafil citrate significantly improves normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy. J Urol, 2003; 169(Suppl. 4): 375.
- Schwartz EJ, Wong P, Graydon RJ. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. J Urol, 2004; 171: 771-774. Go to original source... Go to PubMed...
- Študent V, Hrabec M, Hartmann I, Vidlář A. Současné možnosti farmakologické léčby erektilní dysfunkce. Klin Farmakol Farm 2007; 21: 15-21.
- Raina R, Agareal A, Ausmundson S, et al. Early use of vacuum constriction device following radical prostatectomy facilitates early sexual activity and potentially earlier return of erectile function. Int J Impot Res, 2006; 18: 77-81. Go to original source... Go to PubMed...
- Gontero P, Fontana F, Bagnasacco A, et al. Is there an optimal time for intracavernous prostaglandin E1 rehabilitation following nonnerve sparing radical prostatectomy? Results from a hemodynamic prospective study. J Urol, 2003; 169: 2166-2169. Go to original source... Go to PubMed...
- Mulhall JP, Land S, Parker M, et al. The use of an erectogenic pharmacotherapy regimen following radical prostatectomy improves recovery of spontaneous erectile function. J Sex Med, 2005; 2: 532-542. Go to original source... Go to PubMed...
- Costabile RA, Spevak M, Fishman IJ, et al. Efficacy and safety of transurethral alprostadil in patients with erectile dysfunction following radical prostatectomy. J Urol, 1998; 160: 1325-1328. Go to original source... Go to PubMed...
- Raina R, Agarwal A, Ausmundson S, et al. Longterm efficacy and compliance of MUSE for erectile dysfunction following radical prostatectomy. SHIM (IIEF 5) analysis. Int J Impot Res, 2005; 17: 86-90. Go to original source... Go to PubMed...
- Raina R, Agarwal A, Nandipati KC, et al. Interim analysis of the early use of MUSE following radical prostatectomy (RP) to facilitate early sexual activity and return of spontaneous erectile function. J Urol, 2005; 173(Suppl.): 737. Go to original source...
- Mydlo JH, Viterbo R, Crispen P. Use of combined intracorporal injection and a phosphodiesterase-5 inhibitor therapy for men with a suboptimal response to sildenafil and/or vardenafil monotherapy after radical retropubic prostatectomy. BJU Int, 2005; 95: 843-846. Go to original source... Go to PubMed...
- Zámečník L. Genová terapie - nová naděje v léčbě erektilní dysfunkce? Urol List 2007; 5(3): 34-37.
- Pacík D. Penilní protézy, jejich místo v léčbě erektilní dysfunkce a vlastní dlouhodobé zkušenosti. Urologie pro praxi. 2005; 1: 18-22.