Urolog. pro Praxi, 2009; 10(3): 194-199

Options of contraception in men

MUDr. Vladimír Kubíček CSc^1,2

¹ Centrum andrologické péče, České Budějovice, Centrum reprodukční medicíny GEST, Praha

² Centrum andrologické péče, České Budějovice

Reliable contraceptive methods for men, comparable to modern female methods, have been identified. Selected regimens are under

active development through the collaboration of andrologists, public sector agencies and pharmaceutical industries. Clinical studies

employing prototype drugs have demonstrated that the hormonal approach to switching off spermiogenesis provides contraceptive

efficacy and is reversible with short term safety. No regimen yet achieves consistent azoospermia in all men. Combination regimens

involving a second gonadotropin-supressing agent, usually a progestine, combined with testosterone achieve close to the ideal of

universal supression of spermiogenesis and contraceptive efficacy. Vasectomy is the surrest methos of male contraception, failure rate

is approximately 1 : 1 000. Vasectomy should be regarded as an irreversible procedure. Informed consent form for vasectomy, partner

notification and vasectomy surgeon´s statement is neccesary.

Keywords: male contraception, androgens, gestagens, GnRH agonists and antagonists, occlusion of the vas deferens.

Published: June 1, 2009  Show citation