Urolog. pro Praxi, 2005; 2: 50-54

NTERSTITIAL HDR BRACHYTHERAPY OF PROSTATE CARCINOMA

MUDr. Renata Soumarová Ph.D¹, Mgr. Luboš Homola¹, doc. MUDr. František Záťura CSc², MUDr. Kamil Belej², MUDr. Miroslav Štursa³

¹ Onkologické centrum J. G. Mendela, Nový Jičín

² Urologická klinika FN a LF UP v Olomouci

³ Urologické oddělení, Nemocnice Valašské Meziříčí

Tumours of prostate affect an increasing number of men and thus form serious problem for the whole society. Early detection by means of an investigation of prostate specific antigen (PSA) level and subsequently appropriately performed prostate biopsy enable to detect this disease in a curable localised stage. Therapeutic method of choice in majority of these patients is a radical prostatectomy or a radical irradiation of prostate. Prostate carcinoma belongs among dose dependent tumours, so the higher dose we deliver, the higher is the probability of disease local control. The application of tumoricid dose requires very good technical equipment – the possibility of 3-D planning according to a CT examination, shielding of neighbouring organs and tissues by means of multileaf collimator or the possibility to use intensity modulated radiotherapy (IMRT). The goal is a dose escalation without irradiation of neighbouring healthy organs, a rectum primarily. External beam radiotherapy has its limits and in spite of use of the most advanced technical equipment it is not possible to deliver the dose higher than 80 Gy. Combination of external beam radiotherapy with a brachytherapy or brachytherapy alone enables this dose escalation.

Keywords: Key words: localised prostate carcinoma, brachytherapy, interstitial implantation.

Published: January 1, 2006  Show citation